KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NNT
All Species:
22.42
Human Site:
S75
Identified Species:
54.81
UniProt:
Q13423
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13423
NP_036475.3
1086
113896
S75
N
E
K
R
V
A
L
S
P
A
G
V
Q
N
L
Chimpanzee
Pan troglodytes
XP_001134902
1086
113819
S75
N
E
K
R
V
A
L
S
P
A
G
V
Q
N
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536481
1086
113623
S75
N
E
K
R
V
A
L
S
P
A
G
V
Q
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61941
1086
113820
S75
N
E
K
R
V
A
L
S
P
A
G
V
Q
A
L
Rat
Rattus norvegicus
NP_001013175
1086
113851
S75
N
E
K
R
V
A
L
S
P
A
G
V
Q
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508040
959
99995
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087704
1086
113982
S75
N
E
K
R
V
A
L
S
P
A
G
V
Q
A
L
Zebra Danio
Brachydanio rerio
NP_999921
1079
112765
A73
R
R
V
A
I
S
P
A
G
V
E
A
L
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509028
1041
109661
Y73
N
A
G
V
L
A
G
Y
S
N
E
E
Y
V
R
Sea Urchin
Strong. purpuratus
NP_001116985
1071
113445
A76
F
L
N
E
R
R
V
A
A
A
P
I
A
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
96.5
N.A.
93
93
N.A.
79.7
N.A.
86.7
82.3
N.A.
N.A.
N.A.
60.1
65.1
Protein Similarity:
100
99.8
N.A.
98.4
N.A.
96.2
96
N.A.
84
N.A.
94.1
91.1
N.A.
N.A.
N.A.
73.3
78.8
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
93.3
0
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
93.3
20
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
70
0
20
10
70
0
10
10
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
60
0
10
0
0
0
0
0
0
20
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
10
0
60
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
20
% K
% Leu:
0
10
0
0
10
0
60
0
0
0
0
0
10
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
70
0
10
0
0
0
0
0
0
10
0
0
0
20
0
% N
% Pro:
0
0
0
0
0
0
10
0
60
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% Q
% Arg:
10
10
0
60
10
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
10
0
60
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
10
60
0
10
0
0
10
0
60
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _